We're looking back at the biggest headlines of 2010, and we'll be revealing more throughout the month of December. Here's one of the stories that created the most buzz over the past 12 months; don't miss the rest of our Best of 2010 coverage across the network!

Jennifer Aniston devoted herself to new film projects and good friends in 2010. She kicked off the year by showing off her chemistry with her The Bounty Hunter costar Gerard Butler as they presented at the Golden Globes. In February, Jennifer headed South to celebrate her 41st birthday with a bikini-filled getaway to Cabo, bringing along some girlfriends and a shirtless Gerard for some fun in the sun. The pair fueled romance rumors as they posed for a sexy spread in W Magazine's March issue and got close at premieres and photo calls from NYC to Berlin. Gerard continually denied being in a relationship with Jen, despite some interesting photos from their time in Paris.

Jennifer and Gerard went their separate ways over the Summer, and she was later romantically linked to SNL's Jason Sudeikis and old friend Christopher Gartin. She went on to launch her new perfume in London and had plenty of chances to show off her swimsuit-ready shape on the set of Just Go With It alongside Adam Sandler and Brooklyn Decker in Hawaii. She and Brooklyn even went head to head in this year's bikini bracket, with Jennifer eventually taking the top spot! We delivered the news in person when we sat down with her at The Switch junket in July, when we also chatted about her friend Courteney Cox. Jennifer told us she'd do "anything" for her former Friends costar, and in August, she put in a hilarious cameo on Courteney's show Cougar Town.

Jennifer took a break from shooting Wanderlust in NYC in November and kicked off her holiday season with a Thanksgiving trip to one of her favorite Mexican vacation spots with close friends like Chelsea Handler. It was a whirlwind year for Jennifer professionally and personally, and we'll see more of her in 2011 with Horrible Bosses arriving in theaters.

WireImage, Getty, INFDaily.com, Flynet and Cougar Town image copyright 2010 ABC, Inc.